Candida albicans, M5

Candida albicans (C. albicans) is a unicellular yeast. Besides its allergenic potential, it is an opportunistic pathogen in immunocompromised individuals. C. albicans has three distinct growing features - yeast, pseudo-hyphae, and true hyphae. The cell wall of the fungus is a complicated, multi-faceted, solid structure made up of mannoproteins, β-glucans, and chitin. C. albicans is thermotolerant and a part of normal human microbiota, found at mucosal sites in healthy individuals. They grow in colonies, which are white in color with smooth and creamy texture. C. albicans can adapt and proliferate in various host environments. Ideal environmental conditions for C. albicans hyphal growth are 37°C temperature, presence of serum, neutral pH, and high CO2. In sensitized individuals, C. albicans can induce or worsen life threatening asthma and skin symptoms and atopic dermatitis. Major allergens identified are Cand a 1 and Cand a 3. Cross reactivity of C. albicans allergenic molecules is reported with molds and yeast.

• Postpone the process of testing immediately after paraclinical studies (roentgen, TC, MRI) and physiotherapy procedures. They can affect test results.

• We recommend avoiding physical activity prior to your examination.