Genetic risk of hypertension (9 polymorphisms)
We remind you that independent interpretation of the results is unacceptable, the information provided below is for reference purposes only.
Hypertension or high blood pressure, is a complex condition influenced by various genetic and environmental factors. This analysis examines nine polymorphisms (genetic variations) associated with an increased risk of developing hypertension. Understanding these genetic markers can provide insights into an individual's predisposition to hypertension and potentially guide preventive measures and personalized treatment strategies.
The nine polymorphisms analyzed in this test are associated with genes involved in various physiological processes related to blood pressure regulation, including sodium and water balance, vascular function, and the renin-angiotensin-aldosterone system.
Table 1: Genetic Polymorphisms Associated with Hypertension Risk
| Gen | Description |
|---|---|
| AGT | Angiotenzinogen - Influences angiotensinogen levels |
| ACE | Enzyme involved in the formation of angiotensin II |
| GNB3 | Affects G-protein signaling |
It is important to note that having one or more of these genetic variants does not necessarily mean an individual will develop hypertension. The risk is influenced by the interplay of multiple genetic and environmental factors. However, understanding one's genetic predisposition can aid in implementing preventive measures and adopting a healthier lifestyle to mitigate the risk.
Indications
- Family history of hypertension: Individuals with a strong family history of hypertension may benefit from this assessment to understand their genetic predisposition and take proactive measures to reduce their risk.
- Early detection and prevention: The assessment can be valuable for individuals who wish to identify their risk early and implement lifestyle modifications or other preventive strategies to lower their chances of developing hypertension.
- Personalized treatment approach: For individuals already diagnosed with hypertension, the genetic risk assessment can provide insights into the underlying genetic factors contributing to their condition, allowing healthcare providers to tailor treatment plans accordingly.
- Research and clinical studies: Researchers and clinicians may utilize the Hypertension Genetic Risk Assessment to further understand the genetic basis of hypertension and develop new targeted therapies or interventions.
Procedure
The blood sample for the Genetic Risk of Hypertension (9 Polymorphisms) analysis is typically collected from a vein in the arm. The procedure is performed by a trained medical professional and takes only a few minutes. A small amount of bleeding or bruising may occur at the puncture site, which should resolve within a few days.
Sources:
https://www.ahajournals.org/doi/10.1161/01.HYP.0000065618.56368.24
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267871/
https://karger.com/pls/article/12/1/19/894757/Genetic-Variants-Associated-with-Hypertension-Risk
https://www.nature.com/articles/hr2008330.pdf
IMPORTANT!
It is crucial to remember that the information provided in this section is not intended for self-diagnosis or self-treatment. If you experience any pain or exacerbation of a medical condition, it is imperative to consult a qualified healthcare professional for proper diagnosis and treatment recommendations. Only a licensed medical practitioner can accurately diagnose and prescribe appropriate treatment. To ensure the most accurate and consistent evaluation of test results, it is recommended to have the tests performed at the same laboratory. This is because different laboratories may use varying methods and units of measurement for similar tests.
Pregătirea:
- Avoid intense physical activity on the day of the test, as it may affect the results.
- Refrain from alcohol consumption and smoking one day before the procedure.
- Maintain normal body hydration by drinking enough fluids to facilitate the blood collection procedure.
- Inform your doctor about any medications you are taking, as some may affect the test results.